Sunday 2 June 2019

Trial suggests total neoadjuvant therapy for locally advanced rectal cancer is safe

Results from the first experimental arm using veliparib as part of total neoadjuvant therapy (induction chemotherapy followed by chemoradiotherapy and surgery; TNT) in patients with locally advanced rectal adenocarcinoma on the NRG Oncology Phase II clinical trial NRG-GI002 were recently presented at the American Society of Clinical Oncology (ASCO) Annual Meeting. Results were reported on the primary endpoint of pathological regression via the neoadjuvant rectal cancer (NAR) score, a short-term clinical trial surrogate endpoint.

* This article was originally published here

Sprint launches mobile 5G network in Atlanta, Dallas-Fort Worth, Houston and Kansas City

Sprint is still sweating out regulatory approval for its would-be merger with T-Mobile.

* This article was originally published here

An approach to enhance machine learning explanations

Researchers at IBM Research UK, the U.S. Military Academy and Cardiff University have recently proposed a new approach to improve the sensitivity of LIME (Local Interpretable Model Agnostic Explanations), a technique for attaining a better understanding ofthe conclusions reached by machine learning algorithms. Their paper, published on SPIE digital library, could inform the development of artificial intelligence (AI) tools that provide exhaustive explanations of how they reached a particular outcome or conclusion.

* This article was originally published here

Native plant species may be at greater risk from climate change than non-natives

As spring advances across the Midwest, a new study looking at blooming flowers suggests that non-native plants might outlast native plants in the region due to climate change.

* This article was originally published here

Occupational hazards account for more than one in ten people with range of lung diseases

More than 1 in 10 people with a range of non-cancerous lung diseases may be sick as a result of inhaling vapors, gas, dust or fumes at work, according to a joint American Thoracic Society and the European Respiratory Society statement published in the ATS's American Journal of Respiratory and Critical Care Medicine.

* This article was originally published here

Guidelines updated for radiotherapy after prostatectomy

(HealthDay)—Clinical guidelines on adjuvant and salvage radiotherapy after radical prostatectomy have been updated, according to the American Society for Radiation Oncology and the American Urological Association.

* This article was originally published here