Thursday, 23 May 2019

Studying the function of liver cancer genes in mini-organs

Researchers from the Hubrecht Institute and Radboud University have developed a human model in which they use organoids, or mini organs, to study the function of specific genes that are mutated in liver cancer. Using this method, they have found that mutations in BAP1, a gene commonly mutated in liver cancer, changes the behaviour of the cells, which may make them more likely to be invasive. Their results were published in the scientific journal Cell Stem Cell on the 23 of May.

* This article was originally published here